Autophagy is an evolutionary conserved catabolic process deemed to maintain or restore cellular and organismal homeostasis. In plants, basal autophagy is essential for growth and development, it is required for nutrient remobilization during senescence and nutrient deficiency, for removal of organelles and macromolecules formed during plant development or damaged by environmental stresses. The material to be degraded is delivered to the vacuole within the double-membrane vesicles - autophagosomes that are generated in the cytoplasm when macroautophagy is induced.
Polyamines (PAs) are ubiquitous cell components essential for normal growth of cells being implicated in cell division, differentiation and death, during plant morphogenesis and in response to stresses. The direct relationship between PAs and autophagy has been acknowledged in the yeast, animal and human cells. We have studied the role of PAs in the process of autophagy in two plant model systems tobacco BY 2 cell culture and Norway spruce embryogenic cultures.
Typ publikace
Datum vydání